Cutaneous lupus erythematosus is a type
of lupus that involves the skin but may be a precursor
to the systemic form of the disease. There are three
types of cutaneous lupus erythematosus: acute lupus
erythematosus; subacute lupus erythematosus, and chronic
lupus erythematosus (often called lupus discoid).
The acute type of chronic cutaneous lupus erythematosus
causes a butterfly-shaped rash across the nose and
cheeks as well as other rashes.
The subacute type of chronic cutaneous lupus
erythematosus causes dry, symmetrical, ring-shaped,
superficial lesions that can occur all over the body but
most often occur on the upper back and chest. The rash
does not cause scars and significant systemic disease
manifestations are uncommon.
The chronic type of cutaneous lupus erythematosus is the
most common type of cutaneous lupus erythematosus and
causes red, scaly, coin-shaped lesions on the body
(discoid lesions) which occur mainly on cheeks and nose
but can occur on the upper back, neck, backs of hands,
lips or scalp. The lesions often leave permanent scars
and may cause permanent hair loss if the lesions occur
on the scalp they also cause ulcers and scaling if they
occur on the lips.
The people most likely to be affected
by cutaneous lupus erythematosus are dark skinned women
between the ages of 20 and 50. Often cutaneous lupus
erythematosus lesions occur or get worse after exposure
to the sun. SLE and SCLE may be induced by the long-term
use of certain drugs such as thiazide diuretics,
glyburide, calcium channel blockers (diltiazem,
felodipine) and penicillamine.
Steroidal creams can be used to treat the lesions of
cutaneous lupus erythematosus. The creams are applied to
the lesions two times a day until they disappear. When
the rash is mild, weaker types of cream are available
which are safer to use.
Taelengiectasia can be helped by the use of a vascular
laser. Other treatments include acitretin, thalidomide,
cyclosporin, gold, methotrexate, intravenous
immunoglobulin, clofazamine, dapsone, and
cyclophosphamide.
Cutaneous lupus erythematosus can also be treated with
oral steroids, but are only used in very severe cases of
DLE. These drugs have side negative side effects as
well, so talk to your doctor about your benefits vs. the
risks.
Antimalarial drugs such as chloroquine
and hydroxychloroquine can be used to treat cutaneous
lupus erythematosus. These drugs work by reducing
inflammation but they do have harmful side-effects, so
you will need to have regular eye exams and blood tests.
To prevent and treat cutaneous lupus erythematosus you
should stay indoors between the hours of 10 a.m. and 2
p.m., wear protective clothing and a hat, and use a
sunscreen with SPF of 30 that protects against UVA and
UVB rays.
Sometimes these milder forms of lupus discoid can develop into
the more serious systemic form of the disease, so if you
have one of the forms of cutaneous lupus erythematosus,
it is important to eat a healthy diet, take vitamins, do
not drink or smoke, stay out of the sun as much as
possible and see your dermatologist regularly. In
addition, getting treatment for lupus erythematosus
promptly may help to prevent scars and hair loss from
the lesions of SLE.
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