Glucosamine, chondroitin and MSM are natural substances
that are already in the connective tissues of the human
body. Glucosamine is a type of amino sugars that forms
and repairs cartilage. Chondroitin is a segment of a big
protein molecule (proteoglycan) that gives elasticity to
cartilage. Both glucosamine, chondroitin and MSM have
anti-inflammatory properties in them which are why they
are helpful in treating rheumatic diseases such as
arthritis (inflammation and pain of the joints).
Glucosamine, chondroitin and MSM are supplements that
are used in the treatment of osteoarthritis.
Glucosamine, chondroitin and MSM work to slow the
progression of the disease as well as relieve pain. Pain
relief from these supplements has to do with their
anti-inflammatory properties.
Glucosamine, chondroitin and MSM have been used safely
and effectively for many years in Europe. Those that
take glucosamine, chondroitin and MSM report very few
side effects. They can be found as dietary or
nutritional supplements and available without a
prescription. .
When you purchase glucosamine, chondroitin and MSM,
remember that the quality of the product, the other
ingredients in the supplement, as well as the delivery
system make a big difference in the amount of relief
experienced.
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Glucosamine helps repair cartilage and chondroitin helps
cartilage become more elastic and helps cartilage to
retain more water as well as inhibit the enzymes that
cause cartilage to deteriorate. Four out of five people
that use glucosamine, report a significant reduction in
the pain of osteoarthritis.
Often, chrondoitin is sold in a combination formula for
arthritis along with the supplement glucosamine and
other supplements such as the anti-inflammatory enzyme
bromelain, MSM, sea cucumber, zinc, horsetail, manganese
and boswellia (a tree extract).
Glucosamine sulfate is the number one building block for
the large molecules that are inside cartilage which give
the cartilage buffering properties, called viscoelastic
properties. This buffering is necessary for smooth
movement of the joint. Glucosamine can be taken orally
and it absorbs readily (within four hours) into the
cartilage.
Glucosamine is also helpful for the pain of arthritis
due to the anti-inflammatory properties it contains.
Glucosamine works similarly to anti-inflammatory drugs
such as non-steroidal anti-inflammatory drugs (NSAIDs)
without the negative side effects. Some common NSAIDs
include aspirin and ibuprofen. Past studies have shown
that those taking glucosamine and chondroitin for mild
to moderate osteoarthritis reported pain relief similar
to the pain relief from NSAIDs.
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The following are quotes from Consumer Reports on
glucosamine and chondroitin: “Our medical consultants
say there’s enough evidence to conclude that products
containing the amounts of glucosamine, chrondroitin, or
both what worked in the clinical trials might be worth
trying for people with osteoarthritis—particularly if
they’ve experienced or are likely to experience
significant side effects from conventional painkillers.”
Overall, glucosamine, chondroitin and MSM are safe,
effective treatments for the pain and inflammation of
osteoarthritis. They also are effective in creating and
preventing the deterioration of cartilage.
Glucosamine and chondroitin are not indicated for use in
children, pregnant women or women who can become
pregnant due to a lack of studies of these supplements
on the long term or short term effects on children or
developing fetuses. In addition, if you are taking blood
thinning medications or daily aspirin therapy, if you
take chondroitin, you should have your blood clotting
time checked often because chondroitin may cause blood
thinning and may cause bleeding in some individuals.
Furthermore, if you are allergic to shellfish, you
should consult your doctor before taking glucosamine
because glucosamine is extracted from shellfish.
Generally, there should be no problem since there
allergies are usually caused by the proteins of
shellfish, not the chitin which is a carbohydrate taken
from shellfish.
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