Glucosamine and chondroitin have been used safely and
effectively for many years in Europe. Those that take
glucosamine and chondroitin report very few side
effects. They can be found as dietary or nutritional
supplements and available without a prescription.
Glucosamine comes from lobster crab or shrimp shells and
chondroitin comes from animal cartilage like tracheas or
shark cartilage.
Glucosamine and chondroitin are two supplements that are
used in the treatment of osteoarthritis. Glucosamine and
chondroitin work to slow the progression of the disease
as well as relieve pain. Pain relief from these
supplements has to do with their anti-inflammatory
properties.
The following are quotes from Consumer Reports on
glucosamine and chondroitin: “Our medical consultants
say there’s enough evidence to conclude that products
containing the amounts of glucosamine, chondroitin, or
both what worked in the clinical trials might be worth
trying for people with osteoarthritis—particularly if
they’ve experienced or are likely to experience
significant side effects from conventional painkillers.”
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Glucosamine helps repair cartilage and chondroitin helps
cartilage become more elastic and helps cartilage to
retain more water as well as inhibit the enzymes that
cause cartilage to deteriorate. Four out of five people
that use glucosamine, report a significant reduction in
the pain of osteoarthritis.
Glucosamine and chondroitin are safe, effective
treatments for the pain and inflammation of
osteoarthritis. They also are effective in creating and
preventing the deterioration of cartilage.
Often, chondroitin is sold in a combination formula for
arthritis along with the supplement glucosamine and
other supplements such as the anti-inflammatory enzyme
bromelain, sea cucumber, zinc, horsetail, manganese and
boswellia (a tree extract).
Glucosamine sulfate is the number one building block for
the large molecules that are inside cartilage which give
the cartilage buffering properties, called viscoelastic
properties. This buffering is necessary for smooth
movement of the joint.
Glucosamine and chondroitin are natural substances that
are already in the connective tissues of the human body.
Glucosamine is a type of amino sugars that forms and
repairs cartilage. Chondroitin is a segment of a big
protein molecule (proteoglycan) that gives elasticity to
cartilage. Both glucosamine and chondrotin have
anti-inflammatory properties in them which are why they
are helpful in treating rheumatic diseases such as
arthritis (inflammation and pain of the joints).
Glucosamine is helpful for the pain of arthritis due to
the anti-inflammatory properties it contains.
Glucosamine works similarly to anti-inflammatory drugs
such as non-steroidal anti-inflammatory drugs (NSAIDs)
without the negative side effects. Some common NSAIDs
include aspirin and ibuprofen. Past studies have shown
that those taking glucosamine and chondroitin for mild
to moderate osteoarthritis reported pain relief similar
to the pain relief from NSAIDs.
In
addition, glucosamine has shown to have a protective
effect on cartilage in many studies. These studies have
shown glucosamine helps both build cartilage and prevent
the breakdown of cartilage. Currently, a study is being
done by the National Institute of Health on the slowing
of cartilage damage in those taking glucosamine and
chondroitin. Definitive results are expected soon.
When you purchase glucosamine and chondroitin, remember
that the quality of the product, the other ingredients
in the supplement as well as the delivery system make a
big difference in the amount of relief experienced.
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As
with any natural supplement, it is important to inform
your doctor that you are taking them. Some people think
that “all natural” products and vitamins don’t have to
be reported to the doctor, but this is not true. Your
doctor should be aware of any drugs and supplements you
are taking.
Glucosamine and chondroitin are not indicated for use in
children, pregnant women or women who can become
pregnant due to a lack of studies of these supplements
on the long term or short term effects on children or
developing fetuses. In addition, if you are taking blood
thinning medications or daily aspirin therapy, if you
take chondrotin, you should have your blood clotting
time checked often because chondroitin may cause blood
thinning and may cause bleeding in some individuals.
Furthermore, if you are allergic to shellfish, you
should consult your doctor before taking glucosamine
because glucosamine is extracted from shellfish.
Generally, there should be no problem since there
allergies are usually caused by the proteins of
shellfish, not the chitin which is a carbohydrate taken
from shellfish.
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