People have been turning to growth hormone replacement therapy, not just to cure diseases but for vanity reasons: it may counteract the normal aging process. But an absence of growth hormone can be deadly as it is associated with an increase in cardiovascular risk factors.

Studying growth hormones as a possible cure for fibromyalgia may end up saving the country hundreds of millions of dollars in terms of sick days, health care costs and other associated expenses.

Some of the adverse consequences of adult growth hormone deficiency literally leave fibromyalgia patients begging for a cure: low energy, elevated lipoproteins, reduced plasma volume, cold intolerance, increased mortality, poor general health, reduced cardiac output, increased fat, decreased muscle, decline in quality of life, impaired cognition, dysthymia and reduced exercise capacity.

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A cure for fibromyalgia would mean wiping out many of the symptoms that come with the disease such as exercise intolerance, sleep disturbances, dizziness widespread pain, numbness, fatigue and tingling.

Researches say a cure may be found in growth hormone, a naturally occurring hormone secreted by the pituitary gland. They say levels of growth hormone decline with age. However for people with fibromyalgia, a growth hormone deficiency may be at the root of their illness and the root of a cure.

It is interesting to point that fibromyalgia patients often deal with sleep deprivation by not entering stages 3 and 4 of non-REM sleep. Growth hormone happens to be secreted predominantly during stages 3 and 4 of non-REM sleep which means growth hormone therapy could also be a cure for sleep disturbances.

Growth hormone therapy, which is sometimes used as an athletic performance enhancer and anti-aging treatment, is the closest some scientists have come to a cure for not just fibromyalgia but also chronic fatigue system and possibly even obesity.

Scientists searching for a cure believe defective growth hormone secretion can be blamed on an increased somatostatin tone in the hypothalamus.

Researchers focused on a cure, say adult growth hormone deficiency is linked to a number of symptoms experienced by patients with fibromyalgia from cold intolerance and low energy to decreased lean body mass, muscle weakness, poor general health and inability to concentrate.

They believe growth hormone could lend scientists a hand in finding a cure because growth hormones are important in maintaining muscle homeostasis for fibromyalgia patients.

Indeed, patients with fibromyalgia who undergo adult growth hormone deficiency treatment as a cure have been found to experience an improvement in their energy level, increased muscle strength, decreased pain, improved psychological outlook and quality of life, improved cholesterol and LDL levels and increased exercise capacity.

One recent study conducted at the Oregon Health & Science University showed a connection between growth hormone and fibromyalgia, shedding new hope on a cure.
 

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Researchers discovered fibromyalgia patients have an inability to secrete growth hormone during exercise. Researchers believe the situation for fibromyalgia patients centered on a hypothalamic hormone -- somatostatin – that was likely blocking the release of growth hormone.
Researchers discovered a possible cure in Mestinon, a drug commonly used to treat myasthenia gravis, an autoimmune disease in which people suffer attacks of muscle weakness.

Once fibromyalgia patients took Mestinon they secreted normal amounts of growth hormone when they exercised.

Fibromyalgia has stumped researchers searching for a cure just as chronic fatigue syndrome has baffled scientists. However, a cure may be the light shining at the end of the tunnel as researches examine the link between fibromyalgia and growth hormones.

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