Individuals with fibromyalgia may become familiar with a
second-generation anticonvulsant medication called
Neurontin when their physician prescribes it to them.
Some physicians choose the drug Neurontin for their
fibromyalgia patients due to the fact they believe
Neurontin may reduce restless leg syndrome common in
people with fibromyalgia.
Neurontin also appears to have an effect on slow wave
sleep, and patients with fibromyalgia tend not to enjoy
enough of the deepest, beta brain level of sleep
activity, which leads to sleep deprivation and a feeling
of restlessness.
The generic name for Neurontin is Gabapentin. Since the
drug works to block pain receptors and nerve ending in
the brain and throughout the body, many physicians opt
for Neurontin for their fibromyalgia patients. While
your doctor may prescribe Neurontin for your
fibromyalgia condition, be warned Neurontin has been
known to cause suicidal tendency and psychotic mania in
some people including those with fibromyalgia. If you
are taking Neurontin for your fibromyalgia condition,
you may experience a loss of appetite. Also, you may
feel less sensation during sex while using Neurontin.
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Some of the other potential Neurontin side effects for
people with fibromyalgia include headache, sleepiness,
nausea and dizziness. Viral infections, convulsions,
vomiting/diarrhea and memory loss add to the list of
more serious Neurontin side effects that may be
experienced by fibromyalgia patients.
Since Neurontin may inhibit excess neuronal activity, it
is sometimes prescribed off label for conditions such as
fibromyalgia as well as depression, sleep disorders,
anxiety and migraine headaches.
How does Neurontin work? As a brand name that falls
under the class of an anticonvulsants medication,
Neurontin works by enhancing the actions of gamma-aminobutyric
acid (GABA), a natural brain chemical. GABA, which
inhibits the transmission of nerve signals and reduces
nervous excitation, is a neurotransmitter, which means
it transports messages between brain nerve cells.
The following is a list of some of the common side
effects for fibromyalgia patients who use Neurontin:
dizziness, swelling of arms and legs, nausea,
drowsiness, diarrhea, fever, chills, sore throat,
clumsiness, constipation, tiredness, runny nose and
tremor.
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Some of the severe potential side effects for
fibromyalgia patients who are using Neurontin are:
abnormal thoughts, rash, hives and swelling of mouth,
face, lips or tongue, unusual lumps, memory loss,
convulsions, suicidal thoughts, aggression and anger.
Other less deadly side effects of Neurontin for people
with fibromyalgia include sore throat, ear infection,
weight gain, back pain, increased appetite, nervousness,
abrasions, rash, depression, twitching double vision,
sleeplessness, dental problems, coughing, itching,
vomiting, acne, disturbed speech, muscle aches rapid eye
movements, impotence, confusion, blurred vision and
involuntary eye movements.
If
you are a person suffering with fibromyalgia, you may be
curious about the controversy surrounding the alleged
fraudulent marketing of the drug Neurontin.
Neurontin was approved for sale in the mid-1990s as an
anti-seizure medication for epileptics. Pfizer in recent
years pleaded guilty to U.S. criminal charges of
misbranding Neurontin. The controversy started in 2000,
when Pfizer acquired Warner-Lambert, was accused of
defrauding the government's Medicare and Medicaid
programs by urging doctors to prescribe Neurontin for
off-label purposes.
Pfizer agreed to settle their Neurontin $400 million
marketing suit and the civil charges regarding kickbacks
to motivate physicians to prescribe Neurontin for a
number of patients including those with fibromyalgia.
The settlement came about as part of an investigation
into the practice of government health programs being
billed for the free samples given to physicians for
promotional purposes.
Pfizer was again sued in 2004 over improper marketing of
Neurontin after already being penalized $430 million in
federal and state courts for selling Neurontin. Also in
2004, a petition came forward from Finkelstein &
Partners, a personal-injury law firm in Newburgh, N.Y.,
asking the Food and Drug Administration to act on claims
that Neurontin may be tied to suicidal behavior. The
suits were filed against Pfizer on behalf of people who
committed suicide or attempted it which should make many
patients with fibromyalgia wary of Neurontin.
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