Arthoscopic knee surgery is performed each year at cost of more than a billion dollars. Yet, a study involving a knee simulator surgery researching the effectiveness of arthoscopic surgery shows arthroscopic knee surgery to be as effective as having no surgery at all.

The studies show that arthroscopic surgery is no more helpful than placebo surgery for arthritis of knee issues. Researchers say improvements reported by patients who had real operation and those who had placebo operation were just wishful thinking in both cases.

Prevention is the best of all knee replacement alternatives when dealing with arthritis knee pain. However, if knee pain arthritis symptoms are already severe, carefully weight all other options before deciding to undergo knee surgery.

Below is the full article, published in the New York Times on July 11, 2002, that outlines the arthroscopic knee simulator surgery study, conducted by Houston Veterans Affairs Medical Center and Baylor College of Medicine.

Orthopedists interviewed about study said they have wondered about effectiveness of arthroscopic knee simulator surgery. Editorials in the New England Journal of Medicine, where study was published, said the study met ethical criteria for placebo arthroscopic knee surgery.

The implications of this arthroscopic knee simulator surgery study will hopefully change the way people view arthroscopic knee surgery. If actual surgery for arthritis of knee doesn't work any better than arthrosdcopic knee simulator surgery, then why go through the pain and expense at all? Researchers should rethink doing surgery and put the billions of dollars spent annually on arthroscopic surgery to better use elsewhere.

Folks, please realize that arthoscopic surgery should be a last resort that may or may not benefit you. If you want relief dealing with arthritic knee pain, try Arthritin. Arthritin is highly effective and you do not have to go under the knife to get the benefits! Arthritin works well for many joint pain issues from lumbar spine stenosis to treating dogs joints.

"A Knee Surgery for Arthritis Is Called Sham"
By Gina Kolata
New York Times July 11, 2002

A popular operation for arthritis of knee worked no better than a sham procedure in which patients were sedated while surgeons pretended to operate, researchers are reporting today.

The operation - arthroscopic surgery for the pain and stiffness caused by osteoarthritis - is done on at least 225,000 middle-age and older Americans each year at a cost of more than a billion dollars to Medicare, the Department of Veterans Affairs and private insurers.

It involves making three small incisions in the knee; inserting an arthroscope, a thin instrument that allows surgeons to see the joint; and then flushing debris from the knee or shaving rough areas of cartilage from the joint and then flushing it.

In the study, to be published today in The New England Journal of Medicine, investigators at the Houston Veterans Affairs Medical Center and Baylor College of Medicine report that while patients often said they felt better after the surgery, their improvement was just wishful thinking. Tests of knee functions revealed that the operation had not helped, and those who got the placebo surgery reported feeling just as good as those who had had the real operation.

"Here we are doing all this surgery on people and it's all a sham," said Dr. Baruch Brody, an ethicist at Baylor who helped design the study.

The study dealt only with arthroscopic surgery for osteoarthritis, not with other common knee operations.

After learning of the results, Anthony J. Principi, the secretary of veterans affairs, said yesterday that the study would "change the practice of orthopedic medicine in the United States."

But Veterans Affairs Department officials stopped short of saying they would no longer pay for the surgery. Medicare and private insurers typically review such studies before deciding whether to change their reimbursement practices.

The 180 participants in the study were randomly assigned to have the operation or to have placebo surgery in which surgeons simply made cuts in their knees so the patients would not know if they had the surgery.

After they recovered from the procedures, most patients said their knee pain had improved, and they continued to say they were better for the two years that the researchers followed their progress. But Dr. Nelda P. Wray, who is chief of the section of health services research at Baylor, said, "On the objective scale, no one was better at any time point."

Some orthopedists interviewed about the study said they had wondered for some time about the operation's effectiveness. Dr. Kenneth Fine, an orthopedic surgeon at the George Washington University School of Medicine, said the procedure had long seemed to do nothing for patients' underlying arthritis.

"There are pretty good success rates in terms of patient satisfaction," Dr. Fine said, "but I have always been skeptical."

Dr. William J. Tipton Jr., executive vice president and chief executive of the American Academy of Orthopedic Surgeons, also said he had questioned the operation.

"I'm both a patient and a physician," Dr. Tipton said, explaining that he has osteoarthritis. "My knee is buckling now, but I'm not going to have arthroscopy done. I recognize that it's not going to help."

Still, he said he would like to see the study repeated before doctors decided whether to do the operation.

"Gradually," Dr. Tipton speculated, "physicians would say to their patients: `I know you've seen a lot about arthroscopy, but you know what? It doesn't work very well for osteoarthritis of the knee."

But a past president of the orthopedic surgeons' academy, Dr. Douglas Jackson of Long Beach, Calif., said that the study's population, mostly men in a veterans' hospital, was not typical of what he had seen in his private practice, but that he would tell his patients about their experience.

The research began when an orthopedic surgeon at the Houston veterans' hospital, Dr. J. Bruce Moseley, who is now the team physician for Houston's two professional basketball teams, approached Dr. Wray suggesting a study that would compare washing the knee joint with washing and scraping in patients with arthritis.

Dr. Wray had a bolder idea. "She said, `How do you know that what you are seeing is not a placebo effect?' " Dr. Moseley recalled. "My response was, `This is surgery.' She said, `I hate to tell you this, but surgery may have the biggest placebo effect of all.' "

Placebo studies of surgery are almost never done. Many doctors consider them unethical because patients could undergo risks with no benefits. Working with Dr. Brody, the ethicist, the group tried to make the placebo treatment no more dangerous than daily life. Still, of 324 consecutive patients who were asked to participate, 144 declined.

For those who agreed, the day of surgery meant being wheeled into an operating room while neither they nor any of the medical staff knew what their treatment would be. When they were on the operating table, Dr. Moseley, who did all the operations, opened a sealed envelope telling him whether the patient was to have the surgery or not.

Those in the placebo group received a drug that put them to sleep. Unlike those getting the real operation, they did not have general anesthesia.

Dr. Moseley made small cuts in their knees to simulate an operation. He bent and straightened the knee and asked for surgical instruments, just in case the patient was partly conscious. An assistant sloshed water in a bucket to make the sound of a knee being flushed clean.

The paper in The New England Journal is accompanied by two editorials. One, by Sam Horng and Dr. Franklin G. Miller of the National Institutes of Health, asks whether placebo surgery is unethical. The controversy, they wrote, comes because doctors assume that patients in clinical research should not be put at risk if they cannot benefit, and placebo surgery involves risk.

But, they say, clinical research is different from medical therapy; its aim is not to help those in the study but to help future patients. To be ethical, they say, a study with placebo surgery must meet three criteria: it must not place patients at undue risk; the benefits of learning whether the surgery works must be worth any potential risk to the patients; and the patients must give informed consent.

In the current case, they wrote, all those objectives were met and the study "exemplifies the ethically justified use of placebo surgery."

In the second editorial, Dr. David T. Felson of Boston University and Dr. Joseph Buckwalter of the University of Iowa note that if there were large beneficial effects from the surgery, the study should have found them.

"Although the study may not have been large enough to permit the detection of any small effects," they wrote, "the data presented do not suggest that there were any."

In a telephone interview this week, Dr. Felson, a professor of medicine and a rheumatologist by training, praised the research but said it remained to be seen whether doctors and patients would abandon the procedure.

"There's a pretty good-sized industry out there that is performing this surgery," Dr. Felton said. "It constitutes a good part of the livelihood of some orthopedic surgeons. That is a reality."

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