Vioxx has been linked to the increased risk of blood pressure problems, heart attacks and strokes. Studies showed that Vioxx almost quadruples the risk of heart attacks. In addition to these life-threatening side effects, the side effects of Vioxx can also include kidney and liver damage, high blood pressure and stomach ulcers.

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People seeking arthritis pain relief should carefully evaluate drug medication information and side effects before deciding to take arthritis medication drugs. It is important to note that just because a drug is FDA approved and doctor prescribed does not mean that the drug is safe. Vioxx clearly proves this point.

Vioxx FDA Warnings:
In 2001 the Food and Drug Administration ordered Vioxx manufacturer Merck "to correct false or misleading impressions and information" stemming from a promotional campaign aimed to minimize the known and potential cardiac risks of Vioxx. Below is an excerpt of the Sept. 2001 letter sent to Merck from the FDA. "You have engaged in a promotional campaign for Vioxx that minimizes the potentially serious cardiovascular findings that were observed in the Vioxx Gastrointestinal Outcomes Research (VIGOR) study, and thus, misrepresents the safety profile for Vioxx. Specifically, your promotional campaign discounts the fact that in the VIGOR study, patients on Vioxx were observed to have a four to five fold increase in myocardial infarctions (MIs) compared to patients on the comparator non-steroidal anti-inflammatory drug (NSAID), Naprosyn (Naproxen)...You have also engaged in promotional activities that minimize the Vioxx / Coumadin (warfarin) drug interaction, omit important risk information, make unsubstantiated superiority claims against other NSAIDs, and promote Vioxx for unapproved uses and an unapproved dosing regimen. In addition, in misrepresenting the Vioxx / warfarin drug interaction you also misrepresent Vioxx's safety profile by minimizing the potentially serious risk of significant bleeding that can result from using Vioxx and warfarin concomitantly. Your minimizing the potential risks and misrepresenting the safety profile for Vioxx raise significant health and safety concerns. Your misrepresentation of the safety profile for Vioxx is particularly troublesome because we have previously, in an untitled letter, objected to promotional materials for Vioxx that also misrepresented Vioxx's safety profile."

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 Also in 2001, the American Heart Association, the National Stroke Association and the Arthritis Foundation asked Merck & Co. to further test Vioxx and its associated risk of heart disease and stroke." In 2002 Merck strengthened the warnings, precautions and clinical studies section of the Vioxx labeling to include new cardiovascular and gastroenterological safety information.

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